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Know the plan for problems.

Ask what problems the proposed medicine might cause and whom to call for help. Keep the answers with your care notes.

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Ask about the exact product and your circumstances.

Ask what matters about your other medicines, supplements and health history. Mention pregnancy, breastfeeding or plans for pregnancy when discussing treatment.

The pregnancy instructions in the labels for semaglutide and tirzepatide differ.ag

Ask the clinician to explain the instructions for your medicine. Write down when to send a message and when to get urgent help.

Before patients receive a made-to-order medicine, FDA does not review its safety, quality or effect.b

Take unclear instructions back to the clinician.

FDA has had reports of mistakes with made-to-order semaglutide shots, including cases needing hospital care.c

Ask the person who wrote your prescription and the pharmacist to explain any unclear instructions. Take the medicine's name and its paperwork with you.

A medicine-problem report sent to FDA describes an unwanted health problem during medicine use.d

A report alone cannot show that the drug caused harm or how often harm occurs, FDA says.d

Know when to get emergency help.

A severe allergic reaction can put your life at risk and can start within seconds or minutes.e

Possible signs listed by MedlinePlus, the National Library of Medicine service, include breathing trouble and a swollen tongue or face.e

For signs of a severe allergic reaction, MedlinePlus advises emergency help or a trip to your closest emergency room.e

You can send a report about a medicine problem to MedWatch, FDA's reporting service.f

Sources for this check.

Check the exact name, product or payment terms in the relevant record.

Get the plan for questions and for urgent help.

Spot the reasons to pause